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CS-W001157 4
Total: USD 88.00

4'-[(tert-Butyldimethylsilyloxy)methyl]-2,2,2-trifluoroacetophenone

  • CAS No. 87736-75-2

  • Cat. No. CS-0213788
  • Molecule weight318.41
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4'-[(tert-Butyldimethylsilyloxy)methyl]-2,2,2-trifluoroacetophenone|CS-0213788

Structure of 87736-75-2

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General Information

  • CAS No. 87736-75-2
  • Cat. No. CS-0213788
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₁F₃O₂Si
  • Molecular Weight 318.41
  • Synonym(s) O-tert-Butyldimethylsilyl-benzyl Alcohol 4-(2,2,2-Trifluoroethanone)
  • SMILES FC(F)(F)C(C1=CC=C(CO[Si](C)(C(C)(C)C)C)C=C1)=O

Synthesis

  • Route1

    References

    • Fishwick, Colin W. G.; Sanderson, John M.; Findlay, John B. C. Tetrahedron Letters, 1994 , vol. 35, # 26 p. 4611 - 4614
  • Route2

    References

    • Wiegand, Michaela; Lindhorst, Thisbe K. European Journal of Organic Chemistry, 2006 , # 21 p. 4841 - 4851
  • Route3
    • null|null
      383-63-1
    • Tert-butyl((4-iodobenzyl)oxy)dimethylsilane|CS-0948938
      147283-96-3
    • ~10%
    • 4'-[(tert-Butyldimethylsilyloxy)methyl]-2,2,2-trifluoroacetophenone|CS-0213788
      87736-75-2

    References

    • Nakamoto, Kosuke; Ueno, Yoshihito Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2463 - 2472

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   4.9534
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   4

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