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Structure of 877385-86-9
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2-Cyclopropylthiazole-5-carbaldehyde features a cyclopropyl group fused to a thiazole ring, delivering enhanced lipophilicity and metabolic stability. The aldehyde functionality enables direct conjugation in coupling reactions, facilitating rapid access to bioactive heterocycles under standard conditions.
2-Cyclopropylthiazole-5-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient construction of thiazole-based scaffolds through standard aldehyde transformations. Its cyclopropyl substitution enhances metabolic stability and modulates electronic properties, while the aldehyde group facilitates imine formation, reductive amination, and coupling reactions with nucleophiles. The compound exhibits bench stability and compatibility with common protecting groups, facilitating straightforward purification and integration into multi-step synthetic sequences for targeted API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: