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Structure of 877861-62-6
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Methyl 1,2,3,4-tetrahydroisoquinoline-6-carboxylate hydrochloride offers a stable, moisture-tolerant platform for synthesizing bioactive isoquinoline derivatives. The protonated nitrogen enhances solubility in polar media, while the ester functionality enables direct derivatization. This salt form simplifies handling and storage under standard bench conditions, facilitating integration into multi-step synthetic sequences.
Methyl 1,2,3,4-tetrahydroisoquinoline-6-carboxylate hydrochloride serves as a versatile building block for medicinal chemistry and natural product synthesis. The tetrahydroisoquinoline core provides a rigid, bioactive scaffold, while the methyl ester enables further functionalization via hydrolysis or coupling reactions. The hydrochloride salt enhances solubility and stability in aqueous and polar organic media, facilitating handling and purification. This compound functions effectively in standard transition-metal-catalyzed cross-couplings and reductive aminations, enabling efficient access to complex alkaloid frameworks and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: