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Structure of 87808-48-8
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Methyl 3-fluoro-4-methylbenzoate features a fluorine atom at the meta position and a methyl group at the para position relative to the ester, creating a uniquely electron-deficient aromatic ring. This combination enhances reactivity in electrophilic substitution and improves solubility in polar organic solvents. The compound serves as a key building block in pharmaceutical synthesis, particularly for bioactive heterocycles requiring halogenated aromatic scaffolds.
Methyl 3-fluoro-4-methylbenzoate serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient access to substituted benzene scaffolds. The ortho-fluoro and methyl groups provide orthogonal reactivity for subsequent functionalization via palladium-catalyzed cross-coupling or electrophilic substitution. Its bench-stable nature and compatibility with standard purification methods make it well-suited for multi-step synthesis and process development workflows.
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H319-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: