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Structure of 878197-68-3
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5-Bromoimidazo[1,2-a]pyridine-2-carbaldehyde features a fused heterocyclic core with a bromine substituent and a formyl group at adjacent positions. This combination enables direct functionalization in transition-metal-catalyzed cross-coupling reactions, facilitating rapid access to complex imidazopyridine scaffolds for medicinal chemistry applications. The molecule exhibits robust stability under standard bench conditions and tolerates diverse reaction environments.
5-Bromoimidazo[1,2-a]pyridine-2-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient construction of imidazo[1,2-a]pyridine scaffolds via palladium-catalyzed cross-coupling. The aldehyde functionality facilitates direct derivatization through reductive amination or Grignard addition, while the bromo group supports further functionalization via Suzuki-Miyaura or Negishi coupling. Bench-stable and compatible with standard purification methods, it functions effectively in medicinal chemistry campaigns requiring nitrogen-rich, rigid frameworks.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: