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Structure of 878805-23-3
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3-Cyclopropylpicolinic acid features a cyclopropyl substituent at the 3-position of the picolinic acid scaffold, enhancing lipophilicity and metabolic stability. This structural motif enables efficient integration into bioactive molecules, particularly in medicinal chemistry campaigns targeting CNS disorders and kinase inhibitors. The carboxylic acid group facilitates conjugation and salt formation, supporting solubility and formulation flexibility under standard conditions.
3-Cyclopropylpicolinic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amide coupling and cyclization protocols. Its cyclopropyl substituent enhances metabolic stability and modulates lipophilicity, while the pyridine carboxylic acid core facilitates conjugation with diverse amines and nucleophiles. Bench-stable and readily purified by recrystallization, it functions effectively in both small-molecule synthesis and API intermediate development.
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Lot numbers can be found on the outside label of a product: