2-Chloro-5-nitropyrazine

Name: 2-Chloro-5-nitropyrazine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 87885-45-8
Cat. No. CS-0099406
Purity≥97%
MDL No.MFCD06809591

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 87885-45-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2-Chloro-5-nitropyrazine is a heterocyclic compound featuring a pyrazine core functionalized with chlorine at the 2-position and a nitro group at the 5-position. This electron-deficient scaffold enables direct incorporation into synthetic routes requiring strong acceptor moieties, particularly in pharmaceutical intermediates and agrochemical development. The molecule exhibits enhanced stability under standard bench conditions and facilitates selective coupling reactions via the chloro substituent.

Application

2-Chloro-5-nitropyrazine serves as a versatile building block in medicinal chemistry, enabling efficient functionalization at both the chloro and nitro positions. Its reactivity facilitates nucleophilic substitution and subsequent reduction to amine intermediates, supporting the construction of pyrazine-based heterocycles commonly found in pharmaceutical scaffolds. The compound exhibits good bench stability and compatibility with standard synthetic protocols, making it well-suited for modular synthesis workflows.

General Information

CAS No. 87885-45-8
Cat. No. CS-0099406
Purity ≥97%
MDL No. MFCD06809591
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₂ClN₃O₂
Molecular Weight 159.53
Synonym(s) Pyrazine,2-chloro-5-nitro
SMILES O=[N+](C1=CN=C(Cl)C=N1)[O-]

Computational Chemistry Data

TPSA 68.92
LogP 1.0382
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

Key Words

2-Chloro-5-nitropyrazine sigma2-Chloro-5-nitropyrazine manufacturer2-Chloro-5-nitropyrazine price2-Chloro-5-nitropyrazine structure2-Chloro-5-nitropyrazine SDSbuy 2-Chloro-5-nitropyrazine2-Chloro-5-nitropyrazine supplier2-Chloro-5-nitropyrazine uses2-Chloro-5-nitropyrazine molecular weightprice of 2-Chloro-5-nitropyrazine2-Chloro-5-nitropyrazine chemical name formula of 2-Chloro-5-nitropyrazine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-5-nitropyrazine

CAS No. 87885-45-8

Recommended Products