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CS-W001157 4
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Methyl 1-((tert-butoxycarbonyl)amino)cyclobutanecarboxylate

  • CAS No. 880166-10-9

  • Cat. No. CS-0041864
  • Molecule weight229.27
  • Purity≥97%
  • MDL No.MFCD22418433

*For research and further manufacturing use only, not for direct human use.

Methyl 1-((tert-butoxycarbonyl)amino)cyclobutanecarboxylate|CS-0041864

Structure of 880166-10-9

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General Information

  • CAS No. 880166-10-9
  • Cat. No. CS-0041864
  • Purity ≥97%
  • MDL No. MFCD22418433
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₄
  • Molecular Weight 229.27
  • Synonym(s) methyl 1-{[(tert-butoxy)carbonyl]amino}cyclobutane-1-carboxylate
  • SMILES O=C(OC)C1(CCC1)NC(OC(C)(C)C)=O

Description

Methyl 1-((tert-butoxycarbonyl)amino)cyclobutanecarboxylate features a cyclobutane scaffold bearing a sterically encumbered Boc-protected amine and an ester functional group. This stable, bench-ready building block integrates seamlessly into peptide synthesis and medicinal chemistry workflows, enabling efficient access to constrained cyclic amino acid derivatives through selective deprotection and transformation.

Application

Methyl 1-((tert-butoxycarbonyl)amino)cyclobutanecarboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to cyclobutane-containing scaffolds. The Boc-protected amine and ester functionalities offer orthogonal reactivity, facilitating selective transformations in peptide and heterocyclic synthesis. Its bench-stable nature and compatibility with standard deprotection and coupling protocols make it well-suited for iterative synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   64.63
  • LogP   1.6068
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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