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Structure of 880360-85-0
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Methyl 2-formyl-1H-indole-5-carboxylate features a dual functionalization at the indole core, combining a formyl group at C2 and a methyl ester at C5. This electron-deficient scaffold enables direct incorporation into transition-metal-catalyzed couplings and facilitates rapid diversification via nucleophilic addition or condensation reactions under mild conditions.
Methyl 2-formyl-1H-indole-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to biologically relevant indole scaffolds. The orthogonal functionality of the formyl and ester groups facilitates sequential transformations, including reductive amination, condensation reactions, and transition-metal-catalyzed couplings. Its bench-stable nature and compatibility with standard purification protocols make it well-suited for medicinal chemistry campaigns and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: