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CS-W001157 4
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7-Bromo-4-fluoro-2,3-dihydro-1H-inden-1-one

  • CAS No. 881189-73-7

  • Cat. No. CS-0101334
  • Purity≥98%
  • MDL No.MFCD17677341

*For research and further manufacturing use only, not for direct human use.

7-Bromo-4-fluoro-2,3-dihydro-1H-inden-1-one|CS-0101334

Structure of 881189-73-7

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General Information

  • CAS No. 881189-73-7
  • Cat. No. CS-0101334
  • Purity ≥98%
  • MDL No. MFCD17677341
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆BrFO
  • Molecular Weight 229.05
  • Synonym(s) 7-Bromo-4-fluoro-indan-1-one
  • SMILES O=C1CCC2=C1C(Br)=CC=C2F

Description

7-Bromo-4-fluoro-2,3-dihydro-1H-inden-1-one is a fluorinated, brominated indanone derivative featuring a reactive ketone moiety and electron-deficient aromatic framework. This bench-stable compound integrates readily into synthetic routes requiring halogenated indenone scaffolds, enabling efficient access to functionalized heterocycles in medicinal chemistry and materials synthesis.

Application

7-Bromo-4-fluoro-2,3-dihydro-1H-inden-1-one serves as a versatile building block in medicinal chemistry, enabling efficient construction of substituted indane and indole scaffolds. Its bromo and fluoro substituents facilitate palladium-catalyzed cross-coupling and electrophilic functionalization, while the ketone group supports nucleophilic addition and enolate chemistry. The compound exhibits excellent bench stability and simplifies purification, making it well-suited for iterative synthesis workflows in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.7171
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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