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Structure of 881189-74-8
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6-Bromo-4-fluoro-2,3-dihydro-1H-inden-1-one features a fused bicyclic core with strategically positioned halogen substituents. The bromine at C6 and fluorine at C4 introduce distinct electronic and steric effects, enhancing reactivity in cross-coupling processes. This bench-stable ketone serves as a key intermediate in the synthesis of bioactive heterocycles and functionalized aromatic systems.
6-Bromo-4-fluoro-2,3-dihydro-1H-inden-1-one serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted indene scaffolds via palladium-catalyzed cross-coupling reactions. The molecule combines orthogonal halogen handles—bromine at C6 and fluorine at C4—with a reactive ketone functionality, facilitating sequential functionalization. Bench-stable and compatible with standard reaction conditions, it supports the synthesis of complex heterocycles and bioactive molecules through modular transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: