Amlodipine impurity 4

Name: Amlodipine impurity 4
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CAS No. 88150-62-3
Cat. No. CS-0136897
Purity≥98%
MDL No.MFCD07782096

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 88150-62-3

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Description

2-Pentylfuran is a volatile heterocyclic compound mainly associated with the flavor of reverted soybean oil. It is reported to be formed by the auto-oxidation of linolenic acid.

Application

Phthaloylamlodipine serves as a protected derivative of l-amlodipine, enabling controlled release and improved stability during synthetic manipulations. Its phthaloyl group facilitates orthogonal protection of the primary amine, allowing selective deprotection under mild conditions. This compound functions as a key intermediate in the synthesis of l-amlodipine analogs and related calcium channel blockers, offering enhanced bench stability and compatibility with standard coupling and purification workflows.

General Information

CAS No. 88150-62-3
Cat. No. CS-0136897
Purity ≥98%
MDL No. MFCD07782096
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₈H₂₇ClN₂O₇
Molecular Weight 538.98
Synonym(s) Phthaloyl Amlodipine
SMILES O=C(OC)C1=C(NC(=C(C(=O)OCC)C1C=2C=CC=CC2Cl)COCCN3C(=O)C=4C=CC=CC4C3=O)C

Computational Chemistry Data

TPSA 111.24
LogP 3.6038
H_Acceptors 8
H_Donors 1
Rotatable_Bonds 9

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Ether

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Other aromatic heterocycles compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Building Blocks for Pharmaceutical Ingredients

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Amlodipine impurity 4

CAS No. 88150-62-3

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