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CS-W001157 4
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Methyl 1-(hydroxymethyl)cyclopropane-1-carboxylate

  • CAS No. 88157-42-0

  • Cat. No. CS-W020452
  • Purity≥95%
  • MDL No.MFCD16036399
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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

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Methyl 1-(hydroxymethyl)cyclopropane-1-carboxylate|CS-W020452

Structure of 88157-42-0

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Description

Methyl 1-(hydroxymethyl)cyclopropane-1-carboxylate features a strained cyclopropane ring bearing a hydroxymethyl and ester group, enabling selective functionalization in synthetic routes. The pendant hydroxyl supports derivatization while maintaining stability under standard conditions. This scaffold serves as a key intermediate for bioactive molecule synthesis and cyclopropanoid library development.

Application

Methyl 1-(hydroxymethyl)cyclopropane-1-carboxylate serves as a versatile building block for cyclopropyl-containing scaffolds, enabling direct functionalization at the hydroxymethyl group. Its bench-stable nature and tolerance to common reaction conditions facilitate downstream transformations such as oxidation, protection, and coupling reactions. This compound functions effectively in the synthesis of bioactive molecules and heterocyclic systems where constrained cyclopropyl motifs are required.

General Information

  • CAS No. 88157-42-0
  • Cat. No. CS-W020452
  • Purity ≥95%
  • MDL No. MFCD16036399
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₃
  • Molecular Weight 130.14
  • Synonym(s) Methyl 1-(hydroxymethyl)cyclopropanecarboxylate
  • SMILES COC(=O)C1(CO)CC1

Computational Chemistry Data

  • TPSA   46.53
  • LogP   -0.0681
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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