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Structure of 883901-62-0
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tert-Butyl 3-(4-nitrophenyl)azetidine-1-carboxylate features a strained azetidine core bearing a para-nitroaryl group, enabling direct incorporation into bioactive molecules. The tert-butyl ester delivers stability and convenient deprotection under mild acidic conditions. This bench-stable reagent facilitates efficient synthesis of functionalized heterocycles in medicinal chemistry workflows.
tert-Butyl 3-(4-nitrophenyl)azetidine-1-carboxylate serves as a versatile scaffold for medicinal chemistry campaigns, enabling direct access to functionalized azetidines via mild acidolysis. The tert-butyl carbamate group offers excellent bench stability and facilitates purification, while the para-nitrophenyl moiety provides a robust handle for downstream transformations including reduction, Suzuki coupling, and nucleophilic substitution. Its compatibility with standard synthetic protocols makes it ideal for building complex heterocyclic architectures in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: