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Structure of 884494-73-9
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5-Fluoro-6-methoxy-3-pyridinecarboxaldehyde features a pyridine core functionalized with electron-withdrawing fluorine and methoxy groups, enhancing electrophilicity at the aldehyde site. This combination enables selective coupling in transition-metal-catalyzed reactions and facilitates incorporation into bioactive scaffolds requiring polar, electron-deficient heterocycles.
5-Fluoro-6-methoxy-3-pyridinecarboxaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles via standard condensation and coupling reactions. Its ortho-fluoro and meta-methoxy substituents provide predictable electronic modulation and enhanced metabolic stability, while the aldehyde functionality facilitates efficient derivatization under mild conditions. The compound exhibits excellent bench stability and is compatible with common protecting group strategies, making it ideal for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: