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Structure of 884494-74-0
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2-Chloro-5-fluoroisonicotinic acid is a fluorinated pyridine carboxylic acid featuring strategically positioned halogen substituents. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering enhanced metabolic stability and improved binding affinity in target-directed synthesis. The molecule exhibits favorable solubility profiles under standard conditions and serves as a key intermediate in the development of bioactive compounds.
2-Chloro-5-fluoroisonicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-chloro and para-fluoro substituents provide enhanced reactivity in nucleophilic aromatic substitution and Suzuki coupling reactions, while maintaining bench stability and compatibility with common protecting group strategies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: