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Structure of 884860-63-3
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2-Chlorothiazolo[4,5-c]pyridine is a heterocyclic scaffold featuring a fused thiazole-pyridine core with a chlorine substituent at the 2-position. This electron-deficient system enables direct incorporation into bioactive molecules, offering enhanced metabolic stability and improved binding affinity in medicinal chemistry applications. The compound exhibits excellent bench stability and compatibility with standard coupling protocols.
2-Chlorothiazolo[4,5-c]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its electrophilic chlorine atom enables facile nucleophilic substitution, facilitating the introduction of diverse functional groups under mild conditions. The fused thiazolo-pyridine core provides enhanced metabolic stability and π-conjugation, making it valuable in the synthesis of kinase inhibitors and fluorescent probes. Bench-stable and amenable to standard purification techniques, it functions reliably in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: