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Structure of 885271-22-7
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This 2-(5-fluoro-1H-indazol-3-yl)acetic acid features a fluorinated indazolyl core paired with a carboxylic acid side chain, enabling direct conjugation or metal chelation. The electron-deficient heterocycle enhances binding affinity in target-directed synthesis, while the pendant acid group facilitates derivatization under standard conditions. Bench-stable and moisture-tolerant, it serves as a key scaffold in medicinal chemistry campaigns targeting kinase and receptor systems.
2-(5-Fluoro-1H-indazol-3-yl)acetic acid serves as a versatile building block for medicinal chemistry campaigns, enabling the rapid assembly of indazole-based bioactive molecules. Its carboxylic acid functionality facilitates direct coupling reactions and derivatization under standard conditions, while the 5-fluoro substitution enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability and compatibility with common purification methods, making it well-suited for high-throughput synthesis and structure-activity studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: