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CS-W001157 4
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3-{4-[(tert-butoxy)carbonyl]morpholin-3-yl}propanoic acid

  • CAS No. 885274-05-5

  • Cat. No. CS-0237872
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-{4-[(tert-butoxy)carbonyl]morpholin-3-yl}propanoic acid|CS-0237872

Structure of 885274-05-5

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General Information

  • CAS No. 885274-05-5
  • Cat. No. CS-0237872
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₅
  • Molecular Weight 259.30
  • Synonym(s) 4-Boc-3-(2-carboxy-ethyl)-morpholine
  • SMILES CC(C)(C)OC(=O)N1CCOCC1CCC(=O)O

Description

This morpholine-containing carboxylic acid features a tert-butoxycarbonyl-protected amine, enabling straightforward deprotection and functionalization. The pendant propanoic acid group provides a versatile handle for conjugation, while the electron-rich morpholine ring enhances solubility and stability under standard conditions.

Application

3-{4-[(tert-butoxy)carbonyl]morpholin-3-yl}propanoic acid serves as a versatile building block for morpholine-containing scaffolds in medicinal chemistry. The tert-butyl ester group enables selective deprotection under mild acidic conditions, while the carboxylic acid facilitates amide coupling and conjugation reactions. Its stability under standard bench conditions and compatibility with diverse functional groups support efficient synthesis of peptide-like motifs and heterocyclic intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   76.07
  • LogP   1.4871
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

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