Benzyl 4-iodopiperidine-1-carboxylate

Name: Benzyl 4-iodopiperidine-1-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 885275-00-3
Cat. No. CS-W006399
Molecule weight345.18
Purity≥95%
MDL No.MFCD04115043

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Benzyl 4-iodopiperidine-1-carboxylate|CS-W006399

Structure of 885275-00-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 885275-00-3
Cat. No. CS-W006399
Purity ≥95%
MDL No. MFCD04115043
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₆INO₂
Molecular Weight 345.18
Synonym(s) 1-Piperidinecarboxylicacid, 4-iodo-, phenylmethyl ester
SMILES O=C(N1CCC(I)CC1)OCC2=CC=CC=C2

Description

Benzyl 4-iodopiperidine-1-carboxylate features a reactive iodide at the piperidine ring's 4-position, enabling efficient cross-coupling transformations. The benzyl ester group provides solubility and stability under standard conditions, while the electron-deficient iodine facilitates palladium-catalyzed reactions. This compound serves as a key intermediate in the synthesis of bioactive nitrogen-containing architectures.

Application

Benzyl 4-iodopiperidine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable iodo substituent. The benzyl ester group provides excellent bench stability and facilitates straightforward deprotection under standard hydrogenolysis conditions. Its functional group tolerance supports integration into complex molecular architectures, particularly for constructing piperidine-based scaffolds common in pharmaceutical research.

Synthesis

Route1
- 95798-23-5
- ~%
- In-stock
  
  885275-00-3
References
- Smith, Sean W.; Fu, Gregory C. Angewandte Chemie - International Edition, 2008 , vol. 47, # 48 p. 9334 - 9336

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 29.54
LogP 3.2226
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

Benzyl 4-iodopiperidine-1-carboxylate sigmaBenzyl 4-iodopiperidine-1-carboxylate manufacturerBenzyl 4-iodopiperidine-1-carboxylate priceBenzyl 4-iodopiperidine-1-carboxylate structureBenzyl 4-iodopiperidine-1-carboxylate SDSbuy Benzyl 4-iodopiperidine-1-carboxylateBenzyl 4-iodopiperidine-1-carboxylate supplierBenzyl 4-iodopiperidine-1-carboxylate usesBenzyl 4-iodopiperidine-1-carboxylate molecular weightprice of Benzyl 4-iodopiperidine-1-carboxylateBenzyl 4-iodopiperidine-1-carboxylate chemical name formula of Benzyl 4-iodopiperidine-1-carboxylate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Benzyl 4-iodopiperidine-1-carboxylate

CAS No. 885275-00-3

Recommended Products