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CS-W001157 4
Total: USD 88.00

1,2,5-Oxadiazole-3-carboxylic acid

  • CAS No. 88598-08-7

  • Cat. No. CS-W003930
  • Purity≥98%
  • MDL No.MFCD00604386
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1,2,5-Oxadiazole-3-carboxylic acid|CS-W003930

Structure of 88598-08-7

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Description

1,2,5-Oxadiazole-3-carboxylic acid delivers a rigid, electron-deficient heterocyclic scaffold ideal for bioisostatic replacement in medicinal chemistry. This bench-stable carboxylic acid integrates readily into diverse synthetic pathways, offering enhanced metabolic stability and improved solubility profiles in drug discovery applications.

Application

1,2,5-Oxadiazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its carboxylic acid functionality facilitates direct derivatization or activation for amide bond formation, while the oxadiazole ring imparts metabolic stability and favorable physicochemical properties. The compound exhibits bench stability and compatibility with standard coupling protocols, making it a practical choice for library synthesis and lead optimization workflows.

General Information

  • CAS No. 88598-08-7
  • Cat. No. CS-W003930
  • Purity ≥98%
  • MDL No. MFCD00604386
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₂N₂O₃
  • Molecular Weight 114.06
  • Synonym(s) 1,2,5-Oxadiazole-3-carboxylicacid
  • SMILES OC(=O)c1cnon1

Computational Chemistry Data

  • TPSA   76.22
  • LogP   -0.2322
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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