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Structure of 88598-08-7
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1,2,5-Oxadiazole-3-carboxylic acid delivers a rigid, electron-deficient heterocyclic scaffold ideal for bioisostatic replacement in medicinal chemistry. This bench-stable carboxylic acid integrates readily into diverse synthetic pathways, offering enhanced metabolic stability and improved solubility profiles in drug discovery applications.
1,2,5-Oxadiazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its carboxylic acid functionality facilitates direct derivatization or activation for amide bond formation, while the oxadiazole ring imparts metabolic stability and favorable physicochemical properties. The compound exhibits bench stability and compatibility with standard coupling protocols, making it a practical choice for library synthesis and lead optimization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: