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Structure of 886366-16-1
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This cyclopropanecarboxylic acid derivative features a meta-tolyl substituent that enhances aromatic character and steric bulk. The strained cyclopropane ring imparts unique reactivity, while the carboxylic acid group enables direct functionalization or coupling in synthetic sequences. Bench-stable and moisture-tolerant, it serves as a valuable scaffold for medicinal chemistry and materials synthesis.
1-(m-Tolyl)cyclopropanecarboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and constrained scaffolds. Its cyclopropane ring imparts structural rigidity, while the carboxylic acid functionality facilitates straightforward derivatization via amide, ester, or acyl chloride formation. The meta-tolyl substituent enhances lipophilicity and offers favorable steric profiles for target engagement, making it a practical choice for lead optimization campaigns requiring stable, synthetically accessible intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: