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Structure of 886371-77-3
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5-Bromo-2-(trifluoromethoxy)pyridine features a trifluoromethoxy group that enhances electron-withdrawal and metabolic stability, while the bromine substituent enables efficient cross-coupling. This pyridine scaffold serves as a key building block in medicinal chemistry for constructing bioactive heterocycles under standard conditions.
5-Bromo-2-(trifluoromethoxy)pyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined reactivity at the bromine site. The trifluoromethoxy group imparts enhanced metabolic stability and lipophilicity, while the pyridine scaffold provides a robust platform for further functionalization. Its bench-stable nature and compatibility with standard coupling protocols make it a practical choice for constructing complex heterocyclic architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P264-P270-P330
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Lot numbers can be found on the outside label of a product: