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Structure of 886371-78-4
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4-Fluoropicolinic acid features a fluorinated pyridine ring that enhances metabolic stability and modulates electronic properties. This electron-deficient heterocycle integrates readily into bioactive scaffolds, serving as a key building block in medicinal chemistry for targeted kinase inhibitors and CNS drug candidates.
4-Fluoropicolinic acid serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated heterocyclic scaffolds via standard coupling and cyclization protocols. Its ortho-fluoro substitution enhances metabolic stability and modulates electronic properties, while the carboxylic acid group facilitates direct derivatization or incorporation into peptide-like structures. Bench-stable and readily purified, it functions effectively in both solution-phase synthesis and solid-phase workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: