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Structure of 887144-94-7
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1-Trifluoromethyl-1,2-benziodoxol-3(1H)-one is a bench-stable hypervalent iodine reagent featuring a trifluoromethyl group that enables efficient C–CF₃ bond formation. This electrophilic trifluoromethylation agent integrates seamlessly into synthetic workflows, delivering high functional group tolerance and predictable reactivity under mild conditions.
1-Trifluoromethyl-1,2-benziodoxol-3(1H)-one serves as a stable, bench-ready hypervalent iodine reagent that enables efficient trifluoromethylation of diverse substrates. Its robust functional group tolerance and compatibility with standard reaction conditions facilitate direct C–H, O–H, and N–H trifluoromethylation. The reagent functions as a reliable source of the CF₃⁺ equivalent in synthetic workflows, offering high selectivity and ease of purification, making it ideal for medicinal chemistry and process development applications.
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GHS Pictogram :
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GHS No : GHS07,GHS08
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335-H372
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Precautionary Statements : P260-P264-P271-P302+P352-P305+P351+P338
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Lot numbers can be found on the outside label of a product: