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Structure of 887576-98-9
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6-(Trifluoromethyl)-1H-indazole-3-carboxylic acid features a trifluoromethyl group at the 6-position and a carboxylic acid at the 3-position, conferring enhanced electron-withdrawing character and improved solubility in polar solvents. This scaffold integrates readily into bioactive molecules, particularly in kinase inhibitors and drug candidates requiring high metabolic stability and favorable pharmacokinetic profiles.
6-(Trifluoromethyl)-1H-indazole-3-carboxylic acid serves as a versatile building block for medicinal chemistry campaigns, enabling the construction of bioactive heterocycles through standard amide coupling and derivatization protocols. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid functionality facilitates direct conjugation or salt formation. Bench-stable and compatible with common purification methods, it functions reliably in both small-molecule synthesis and high-throughput screening workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: