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Structure of 887580-55-4
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This acetic acid derivative features a 2-chloropyridin-4-yl group that enhances electron-withdrawing character and facilitates coupling reactions. The pendant carboxylic acid enables direct conjugation to amine-functionalized substrates, supporting efficient synthesis of bioactive compounds in medicinal chemistry workflows.
2-(2-Chloropyridin-4-yl)acetic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-containing scaffolds through standard functional group transformations. Its chlorine substituent facilitates palladium-catalyzed cross-coupling reactions, while the carboxylic acid group supports direct amidation or esterification. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for scalable synthesis and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: