Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Tert-butyl 4-(piperazine-1-carbonyl)piperidine-1-carboxylate

  • CAS No. 887587-18-0

  • Cat. No. CS-0461006
  • Purity≥98%
  • MDL No.MFCD07367784
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Tert-butyl 4-(piperazine-1-carbonyl)piperidine-1-carboxylate|CS-0461006

Structure of 887587-18-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

Tert-butyl 4-(piperazine-1-carbonyl)piperidine-1-carboxylate is a bifunctional building block featuring a piperazine ring tethered to a piperidine core via a carbonyl linker. This structure integrates a protected amine and a flexible, electron-rich heterocyclic system, enabling efficient incorporation into complex scaffolds. The tert-butyl ester group offers stability under basic conditions while permitting straightforward deprotection. The molecule's solubility in common organic solvents and robustness in multistep synthesis streamline its use in medicinal chemistry campaigns targeting CNS-active compounds and kinase inhibitors.

Application

Tert-butyl 4-(piperazine-1-carbonyl)piperidine-1-carboxylate serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient construction of complex piperazine-containing scaffolds. The tert-butyl carbamate group provides excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. The piperazine moiety offers multiple points for functionalization, while the piperidine core supports diverse transformations, including alkylation, acylation, and transition-metal-catalyzed coupling reactions, making it ideal for library synthesis and lead optimization workflows.

General Information

  • CAS No. 887587-18-0
  • Cat. No. CS-0461006
  • Purity ≥98%
  • MDL No. MFCD07367784
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₇N₃O₃
  • Molecular Weight 297.40
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CCC(C(=O)N2CCNCC2)CC1

Computational Chemistry Data

  • TPSA   61.88
  • LogP   1.0653
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 887587-18-0 sigma887587-18-0 manufacturer887587-18-0 price887587-18-0 structure887587-18-0 SDSbuy 887587-18-0887587-18-0 supplier887587-18-0 uses887587-18-0 molecular weightprice of 887587-18-0887587-18-0 chemical name formula of 887587-18-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label