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Structure of 888214-21-9
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2-Bromo-1-iodo-3-methylbenzene features a sterically accessible aromatic core with complementary halogen handles, enabling sequential cross-coupling strategies in transition-metal-catalyzed transformations. The methyl group enhances solubility and stabilizes the aromatic framework under standard reaction conditions.
2-Bromo-1-iodo-3-methylbenzene serves as a versatile diaryl building block for palladium-catalyzed cross-coupling reactions. The orthogonal halogen reactivity enables sequential functionalization, with bromine typically undergoing Suzuki or Stille coupling prior to iodine participation. Bench-stable and readily purified by flash chromatography, it facilitates efficient access to substituted biaryls and complex heterocyclic scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: