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Structure of 889865-47-8
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4-Iodo-1-methylpyridin-2(1H)-one features a pyridinone core with a strategically positioned iodine atom and methyl group, enabling direct functionalization in cross-coupling reactions. The electron-deficient ring system enhances reactivity in palladium-catalyzed transformations, while the bench-stable nature supports reliable handling under standard conditions.
4-Iodo-1-methylpyridin-2(1H)-one serves as a versatile building block in cross-coupling chemistry, enabling efficient C–C bond formation via palladium-catalyzed reactions. The iodide group provides high reactivity in Suzuki, Stille, and Negishi couplings, while the pyridinone scaffold offers hydrogen-bonding capability and metabolic stability. Bench-stable and readily purified by crystallization, it functions effectively in medicinal chemistry campaigns and heterocyclic synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: