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CS-W001157 4
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6-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid

  • CAS No. 889939-56-4

  • Cat. No. CS-0054746
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid|CS-0054746

Structure of 889939-56-4

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General Information

  • CAS No. 889939-56-4
  • Cat. No. CS-0054746
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₇NO₄S
  • Molecular Weight 283.34
  • Synonym(s) 6-BOC-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID
  • SMILES CC(C)(C)OC(=O)N1CCC2=C(C1)SC=C2C(O)=O

Description

6-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid is a heterocyclic building block featuring a protected carboxylic acid and a saturated thienopyridine core. This bench-stable scaffold integrates readily into medicinal chemistry campaigns, offering a rigid, electron-rich platform for diversification via deprotection or cross-coupling.

Application

6-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles, particularly in medicinal chemistry campaigns targeting kinase inhibitors and CNS modulators. The Boc-protected amine and carboxylic acid functionality enable orthogonal derivatization, while the tetrahydrothienopyridine core provides a rigid, lipophilic scaffold with favorable metabolic stability. Its bench-stable nature and compatibility with standard coupling and deprotection protocols facilitate efficient route development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.7395
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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