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CS-W001157 4
Total: USD 88.00

3-(Benzyloxy)-5-bromo-2-chloropyridine

  • CAS No. 891785-18-5

  • Cat. No. CS-0156194
  • Purity≥97%
  • MDL No.MFCD26403034

*For research and further manufacturing use only, not for direct human use.

3-(Benzyloxy)-5-bromo-2-chloropyridine|CS-0156194

Structure of 891785-18-5

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General Information

  • CAS No. 891785-18-5
  • Cat. No. CS-0156194
  • Purity ≥97%
  • MDL No. MFCD26403034
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₉BrClNO
  • Molecular Weight 298.56
  • Synonym(s) 5-bromo-2-chloro-3-benzyloxypyridine
  • SMILES C1=CC=C(C=C1)COC2=C(Cl)N=CC(=C2)Br

Synthesis

  • Route1
    • null|null
      552330-34-4
    • ~92%
    • In-stock
      3-(Benzyloxy)-5-bromo-2-chloropyridine|CS-0156194
      891785-18-5

    References

    • Breteche, Anne; Marchand, Pascal; Nourrisson, Marie-Renee; Hautefaye, Patrick; De Nanteuil, Guillaume; Duflos, Muriel Tetrahedron, 2011 , vol. 67, # 26 p. 4767 - 4773
  • Route2
    • In-stock
      5-Bromo-2-chloropyridin-3-ol|CS-W003542
      286946-77-8
    • null|null
      100-39-0
    • ~93%
    • In-stock
      3-(Benzyloxy)-5-bromo-2-chloropyridine|CS-0156194
      891785-18-5

    References

    • MERCK SHARP and DOHME CORP.; WOLKENBERG, Scott; BARROW, James, C.; HARRISON, Scott, T.; TROTTER, B. Wesley; NANDA, Kausik, K.; MANLEY, Peter, J.; ZHAO, Zhijian Patent: WO2011/109261 A1, 2011 ; Location in patent: Page/Page column 37 ;
  • Route3

    References

    • Zhu, Gui-Dong; Gong, Jianchun; Claiborne, Akiyo; Woods, Keith W.; Gandhi, Viraj B.; Thomas, Sheela; Luo, Yan; Liu, Xuesong; Shi, Yan; Guan, Ran; Magnone, Shayna R.; Klinghofer, Vered; Johnson, Eric F.; Bouska, Jennifer; Shoemaker, Alexander; Oleksijew, Anatol; Stoll, Vincent S.; Jong, Ron De; Oltersdorf, Tilman; Li, Qun; Rosenberg, Saul H.; Giranda, Vincent L. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 12 p. 3150 - 3155

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   4.0765
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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