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CS-W001157 4
Total: USD 88.00

Ethyl 5,5,5-trifluoro-2,4-dioxopentanoate

  • CAS No. 893643-18-0

  • Cat. No. CS-0097346
  • Purity≥97%
  • MDL No.MFCD08559044
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Ethyl 5,5,5-trifluoro-2,4-dioxopentanoate|CS-0097346

Structure of 893643-18-0

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Description

Ethyl 5,5,5-trifluoro-2,4-dioxopentanoate features a trifluoromethyl group flanking a β-keto ester motif, delivering enhanced electrophilicity and stability. This electron-deficient enone system facilitates efficient Michael additions and condensation reactions under mild conditions. The molecule's bench-stable nature and solubility in common organic solvents streamline integration into synthetic sequences for complex molecule assembly.

Application

Ethyl 5,5,5-trifluoro-2,4-dioxopentanoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to fluorinated carbonyl-containing scaffolds. Its trifluoromethyl group enhances electrophilicity at the β-position, facilitating nucleophilic additions and condensations under mild conditions. The molecule exhibits bench stability and compatibility with common functional groups, making it well-suited for modular synthesis of fluorinated heterocycles and bioactive intermediates.

General Information

  • CAS No. 893643-18-0
  • Cat. No. CS-0097346
  • Purity ≥97%
  • MDL No. MFCD08559044
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇F₃O₄
  • Molecular Weight 212.12
  • Synonym(s) 5,5,5-TRIFLUORO-2,4-DIOXO-PENTANOIC ACID ETHYL ESTER
  • SMILES O=C(OCC)C(CC(C(F)(F)F)=O)=O

Computational Chemistry Data

  • TPSA   60.44
  • LogP   0.6401
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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