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CS-W001157 4
Total: USD 88.00

5-Formylnicotinic acid

  • CAS No. 893723-55-2

  • Cat. No. CS-0132499
  • Purity≥97%
  • MDL No.MFCD06254754

*For research and further manufacturing use only, not for direct human use.

5-Formylnicotinic acid|CS-0132499

Structure of 893723-55-2

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General Information

  • CAS No. 893723-55-2
  • Cat. No. CS-0132499
  • Purity ≥97%
  • MDL No. MFCD06254754
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅NO₃
  • Molecular Weight 151.12
  • Synonym(s) None
  • SMILES O=C(C1=CC(C=O)=CN=C1)O

Description

5-Formylnicotinic acid features a pyridine ring with strategically positioned formyl and carboxylic acid groups, enabling direct incorporation into bioconjugation workflows. The electron-deficient aromatic core supports efficient coupling reactions, while the formyl moiety offers a reactive handle for hydrazine- or amine-based derivatization under mild conditions.

Application

5-Formylnicotinic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation of both aldehyde and carboxylic acid functionalities into heterocyclic scaffolds. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient synthesis of bioactive molecules, including pyridine-based pharmaceutical intermediates and ligands for metal coordination. The aldehyde group permits selective transformations such as reductive amination or hydrazone formation, while the carboxylic acid supports amide and ester derivatization under routine conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

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Computational Chemistry Data

  • TPSA   67.26
  • LogP   0.5923
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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