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Structure of 894074-82-9
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3-Chloro-6-methylpicolinic acid features a chlorinated pyridine core with a methyl group at the 6-position, delivering enhanced electron-withdrawing character and steric bulk. This combination improves metabolic stability and facilitates selective coupling in synthetic applications. The carboxylic acid functionality enables direct conjugation or derivatization under standard conditions.
3-Chloro-6-methylpicolinic acid serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through standard coupling and cyclization reactions. Its ortho-chloro and methyl substituents provide enhanced reactivity and metabolic stability, while the carboxylic acid functionality facilitates direct derivatization or amide formation. The compound exhibits good bench stability and is readily purified by recrystallization, making it suitable for scale-up and routine synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: