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Structure of 89489-53-2
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Tetrahydro-2H-thiopyran-4-carboxylic acid features a saturated thiacyclic core with a carboxylic acid group at the 4-position, offering a polar, bench-stable scaffold for synthetic applications. The sulfur atom enhances solubility and provides a site for selective functionalization. This moiety integrates readily into bioactive molecule design, particularly in medicinal chemistry campaigns targeting metabolic stability and membrane permeability.
Tetrahydro-2H-thiopyran-4-carboxylic acid serves as a versatile chiral building block for medicinal chemistry and natural product synthesis. Its rigid heterocyclic framework provides defined stereochemistry, while the carboxylic acid functionality enables straightforward derivatization via amide, ester, or acyl chloride formation. The molecule exhibits excellent bench stability and facilitates orthogonal functional group manipulation, making it well-suited for multi-step synthetic sequences and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: