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Structure of 89536-84-5
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N-(tert-Butoxycarbonyl)-N-methyl-D-leucine features a sterically hindered tert-butyl carbamate protecting group and a methylated nitrogen, enabling stable incorporation into peptide sequences. This D-amino acid derivative supports efficient synthesis of non-natural peptides with enhanced metabolic stability and resistance to proteolytic degradation under standard conditions.
N-(tert-Butoxycarbonyl)-N-methyl-D-leucine serves as a robust chiral building block for peptide synthesis, offering enhanced stability and orthogonal protection. The Boc group enables mild acidic deprotection, while the N-methyl substitution reduces amide hydrogen bonding, improving solubility and membrane permeability in peptidomimetic applications. Its D-leucine backbone provides stereochemical control in constrained peptide architectures, facilitating efficient coupling and purification in standard solid-phase workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: