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Structure of 89776-57-8
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1,2-Dimethyl-1H-pyrrole-3-carboxylic acid features a sterically hindered pyrrole core with dual methyl substitutions enhancing electronic density at the C2 position. The carboxylic acid group enables direct coupling in peptide synthesis and serves as a handle for derivatization. This bench-stable, moisture-tolerant reagent integrates readily into bioactive molecule scaffolds.
1,2-Dimethyl-1H-pyrrole-3-carboxylic acid serves as a versatile building block in heterocyclic synthesis, offering a readily functionalizable pyrrole core with orthogonal reactivity. The carboxylic acid group enables direct derivatization via amide coupling or esterification, while the methyl substituents enhance stability and influence regioselectivity in electrophilic substitution. Its bench-stable nature and compatibility with standard purification methods make it suitable for use in medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: