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CS-W001157 4
Total: USD 88.00

1H-Pyrrolo[2,3-b]pyridine-6-carbaldehyde

  • CAS No. 898746-46-8

  • Cat. No. CS-W006067
  • Purity≥98%
  • MDL No.MFCD08689966

*For research and further manufacturing use only, not for direct human use.

1H-Pyrrolo[2,3-b]pyridine-6-carbaldehyde|CS-W006067

Structure of 898746-46-8

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General Information

  • CAS No. 898746-46-8
  • Cat. No. CS-W006067
  • Purity ≥98%
  • MDL No. MFCD08689966
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O
  • Molecular Weight 146.15
  • Synonym(s) 1H-pyrrolo[2,3-b]pyridine-6-carboxaldehyde
  • SMILES O=CC1=CC=C2C(NC=C2)=N1

Description

1H-Pyrrolo[2,3-b]pyridine-6-carbaldehyde features a fused heterocyclic core with a reactive aldehyde handle at the 6-position, enabling direct incorporation into conjugation workflows. The electron-deficient pyrrolopyridine scaffold supports efficient coupling under mild conditions, offering enhanced stability and solubility in polar organic media. This compound serves as a valuable building block for bioactive molecule synthesis.

Application

1H-Pyrrolo[2,3-b]pyridine-6-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient access to bioactive scaffolds through standard carbonyl transformations. Its aldehyde functionality facilitates reductive amination, Wittig reactions, and nucleophilic addition, while the fused pyrrolopyridine core provides structural rigidity and enhanced π-conjugation. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it well-suited for medicinal chemistry campaigns and process-scale applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   1.3754
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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