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Structure of 89892-22-8
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7-Bromoquinazoline serves as a key heterocyclic scaffold in medicinal chemistry, featuring a bromine substituent at the 7-position that enables facile functionalization via cross-coupling reactions. This electron-deficient quinazoline core integrates readily into kinase inhibitor designs and other bioactive architectures, offering enhanced reactivity and metabolic stability under standard bench conditions.
7-Bromoquinazoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biaryl scaffolds. Its bromine substituent provides high reactivity in Suzuki, Stille, and Negishi couplings, facilitating efficient synthesis of complex quinazoline derivatives. The compound exhibits excellent bench stability and compatibility with diverse functional groups, making it well-suited for iterative synthetic strategies in drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: