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Structure of 900026-37-1
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This 3-(2-chloro-4-methoxyphenyl)propanoic acid features a chlorinated methoxyaryl moiety linked to a propanoic acid chain, delivering enhanced lipophilicity and metabolic stability. The para-methoxy group imparts electron-donating character, while the ortho-chloro substitution introduces steric and electronic modulation. This structural motif supports integration into bioactive scaffolds requiring balanced solubility and membrane permeability.
3-(2-Chloro-4-methoxyphenyl)propanoic acid serves as a key building block for bioactive heterocycles and pharmaceutical intermediates, offering a robust platform for Suzuki-Miyaura and Stille coupling reactions. The ortho-chloro and para-methoxy substituents provide orthogonal reactivity, enabling sequential functionalization. Bench-stable and amenable to standard purification methods, it functions effectively in late-stage diversification workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: