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Structure of 900158-99-8
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This protected pyrrolidine carboxylic acid features a sterically hindered diastereoselective scaffold with a tert-butoxycarbonyl group that enables stable, high-yield coupling in peptide synthesis. The dimethyl substitution enhances conformational rigidity and resistance to racemization under standard conditions.
1-(Tert-butoxycarbonyl)-5,5-dimethylpyrrolidine-2-carboxylic acid serves as a stable, bench-ready building block for the synthesis of pyrrolidine-based scaffolds. The tert-butyl carbamate (Boc) group enables straightforward protection and deprotection under mild acidic conditions, while the geminal dimethyl substitution enhances conformational rigidity and metabolic stability. This compound facilitates efficient amide coupling and cyclization reactions, making it particularly valuable in the construction of cyclic peptides and bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: