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CS-W001157 4
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(2-Oxo-1,2-dihydropyridin-4-yl)boronic acid

  • CAS No. 902148-83-8

  • Cat. No. CS-0082335
  • Molecule weight138.92
  • Purity≥96%
  • MDL No.MFCD11223187

*For research and further manufacturing use only, not for direct human use.

(2-Oxo-1,2-dihydropyridin-4-yl)boronic acid|CS-0082335

Structure of 902148-83-8

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General Information

  • CAS No. 902148-83-8
  • Cat. No. CS-0082335
  • Purity ≥96%
  • MDL No. MFCD11223187
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆BNO₃
  • Molecular Weight 138.92
  • Synonym(s) (2-Hydroxypyridin-4-yl)boronic acid
  • SMILES OB(C(C=CN1)=CC1=O)O

Description

This boronate moiety integrates readily into Suzuki-Miyaura couplings, delivering pyridine-based scaffolds with high functional group tolerance. The electron-deficient pyridine ring enhances reactivity in cross-coupling processes, while the pendant ketone enables downstream derivatization. Bench-stable and moisture-tolerant, it simplifies handling in synthetic workflows.

Application

(2-Oxo-1,2-dihydropyridin-4-yl)boronic acid serves as a versatile building block for the synthesis of pyridine-containing scaffolds, enabling direct Suzuki-Miyaura coupling reactions under mild conditions. Its boronic acid functionality offers excellent bench stability and compatibility with diverse functional groups, facilitating efficient access to medicinally relevant heterocycles and advanced intermediates in small-molecule discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   73.32
  • LogP   -1.9453
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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