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Structure of 90253-21-7
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4-Cyclopropyl-1H-pyrazole features a cyclopropyl group at the 4-position of the pyrazole ring, imparting enhanced lipophilicity and metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key pharmacophore in medicinal chemistry. The strained cyclopropyl moiety contributes to conformational rigidity, improving target binding affinity.
4-Cyclopropyl-1H-pyrazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of diverse scaffolds through standard functionalization at the 1- and 3-positions. Its cyclopropyl substituent enhances metabolic stability and modulates lipophilicity, offering favorable physicochemical properties for drug discovery. The pyrazole core exhibits robust bench stability, compatibility with common coupling reactions, and ease of purification—making it a practical choice for high-throughput synthesis and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: