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Structure of 902772-13-8
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5-Bromo-1H-indole-2-carbonitrile features a bromine substituent at the 5-position and a nitrile group at the 2-position of the indole core, enabling direct incorporation into diverse heterocyclic scaffolds. This bench-stable, moisture-tolerant building block facilitates efficient access to functionalized indoles via cross-coupling and nucleophilic addition reactions under standard conditions.
5-Bromo-1H-indole-2-carbonitrile serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established reactivity at the bromine site. The nitrile group provides orthogonal functionality for further derivatization, while the indole core offers structural relevance to bioactive scaffolds. Its bench-stable nature and compatibility with standard purification protocols make it ideal for modular synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: