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Structure of 90347-66-3
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Methyl 3-iodo-4-methylbenzoate features a para-methyl group and a meta-iodo substituent on the aromatic ring, delivering enhanced electrophilic reactivity for palladium-catalyzed cross-coupling reactions. The ester functionality provides solubility in common organic solvents and stability under standard bench conditions, enabling efficient incorporation into complex molecular architectures.
Methyl 3-iodo-4-methylbenzoate serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. The iodide group facilitates reliable Suzuki, Stille, and Negishi couplings under standard conditions, while the methyl and ester functionalities provide orthogonal handles for further functionalization. Bench-stable and readily purified by column chromatography, it is well-suited for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: