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CS-W001157 4
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5-Bromo-2-fluoro-3-methylbenzaldehyde

  • CAS No. 903875-64-9

  • Cat. No. CS-0153724
  • Purity≥97%
  • MDL No.MFCD11110261
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-fluoro-3-methylbenzaldehyde|CS-0153724

Structure of 903875-64-9

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Description

5-Bromo-2-fluoro-3-methylbenzaldehyde features a trifunctional aromatic core with bromine, fluorine, and methyl groups positioned for selective downstream coupling. The aldehyde functionality enables direct integration into Suzuki-Miyaura and Ullmann-type transformations. This electron-deficient aryl scaffold offers enhanced reactivity in cross-coupling workflows while maintaining bench-stable handling characteristics under standard conditions.

Application

5-Bromo-2-fluoro-3-methylbenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted heterocycles and functionalized aromatic scaffolds. The ortho-fluoro and meta-bromo substituents provide orthogonal reactivity for palladium-catalyzed cross-coupling and electrophilic substitution, while the aldehyde group facilitates imine formation, reductive amination, and condensation reactions. Bench-stable and compatible with standard purification protocols, it functions reliably in multi-step syntheses requiring precise regiocontrol.

General Information

  • CAS No. 903875-64-9
  • Cat. No. CS-0153724
  • Purity ≥97%
  • MDL No. MFCD11110261
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BrFO
  • Molecular Weight 217.04
  • Synonym(s) 5-Bromo-2-?uoro-3-methylbenzaldehyde
  • SMILES CC1=C(C(=CC(=C1)Br)C=O)F

Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.70912
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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