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Structure of 905583-06-4
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This boronic acid features a trifluorinated aryl core with a methoxy substituent at the ortho position, delivering enhanced stability and solubility in polar organic solvents. The electron-deficient ring facilitates efficient Suzuki-Miyaura coupling under mild conditions, enabling rapid assembly of complex heterocycles and biaryl architectures in medicinal chemistry workflows.
(3,4-Difluoro-2-methoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its fluorinated aryl core enhances metabolic stability and modulates electronic properties, while the methoxy group provides ortho-directing capability and improved solubility. The boronic acid functionality offers excellent bench stability and compatibility with diverse reaction conditions, facilitating straightforward purification and broad functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: