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Structure of 90721-27-0
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Benzofuran-5-carboxylic acid features a fused heterocyclic core with a carboxylic acid group at the 5-position, enabling direct conjugation in synthetic transformations. This electron-deficient scaffold integrates readily into bioactive molecule design, offering enhanced solubility and metabolic stability compared to simple aromatic acids.
Benzofuran-5-carboxylic acid serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization at the carboxyl group for amide, ester, or acyl chloride derivatization. Its fused heterocyclic structure provides enhanced rigidity and metabolic stability, making it valuable in API synthesis. The compound exhibits good bench stability, facilitates straightforward purification via recrystallization, and demonstrates compatibility with standard coupling reagents in peptide and macrocyclic scaffold construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: