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CS-W001157 4
Total: USD 88.00

4-Bromonaphthalene-1-sulfonamide

  • CAS No. 90766-48-6

  • Cat. No. CS-0270247
  • Molecule weight286.15
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromonaphthalene-1-sulfonamide|CS-0270247

Structure of 90766-48-6

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General Information

  • CAS No. 90766-48-6
  • Cat. No. CS-0270247
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BrNO₂S
  • Molecular Weight 286.15
  • Synonym(s) 4-Bromo-naphthalene-1-sulfonic acid amide
  • SMILES C1=CC=C2C(=C1)C(=CC=C2S(=O)(=O)N)Br

Description

4-Bromonaphthalene-1-sulfonamide features a brominated naphthalene core paired with a sulfonamide group, delivering enhanced solubility and stability in polar reaction media. This combination enables efficient coupling reactions and facilitates incorporation into bioactive scaffolds for medicinal chemistry applications.

Application

4-Bromonaphthalene-1-sulfonamide serves as a versatile building block for the synthesis of biologically active heterocycles and pharmaceutical intermediates. The bromo group enables palladium-catalyzed cross-coupling reactions, while the sulfonamide functionality provides a polar, hydrogen-bonding handle compatible with diverse functional group transformations. This compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

  • TPSA   60.16
  • LogP   2.2497
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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